Chromosome-breakage genomic instability and chromothripsis in breast cancer

BACKGROUND: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data observed by array comparative genomic hybridizat...

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Vydáno v:BMC Genomics
Hlavní autoři: Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://ncbi.nlm.nih.gov/pubmed/25011954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-579
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