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Chromosome-breakage genomic instability and chromothripsis in breast cancer

BACKGROUND: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data observed by array comparative genomic hybridizat...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://ncbi.nlm.nih.gov/pubmed/25011954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-579
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