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Emerging Technologies for Genome-Wide Profiling of DNA Breakage

Genome instability is associated with myriad human diseases and is a well-known feature of both cancer and neurodegenerative disease. Until recently, the ability to assess DNA damage—the principal driver of genome instability—was limited to relatively imprecise methods or restricted to studying pred...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Rybin, Matthew J., Ramic, Melina, Ricciardi, Natalie R., Kapranov, Philipp, Wahlestedt, Claes, Zeier, Zane
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873462/
https://ncbi.nlm.nih.gov/pubmed/33584810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610386
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