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Emerging Technologies for Genome-Wide Profiling of DNA Breakage

Genome instability is associated with myriad human diseases and is a well-known feature of both cancer and neurodegenerative disease. Until recently, the ability to assess DNA damage—the principal driver of genome instability—was limited to relatively imprecise methods or restricted to studying pred...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Rybin, Matthew J., Ramic, Melina, Ricciardi, Natalie R., Kapranov, Philipp, Wahlestedt, Claes, Zeier, Zane
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873462/
https://ncbi.nlm.nih.gov/pubmed/33584810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610386
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