Quantitative analysis of male germline stem cell differentiation reveals a role for the p53-mTORC1 pathway in spermatogonial maintenance

p53 protects cells from DNA damage by inducing cell-cycle arrest upon encountering genomic stress. Among other pathways, p53 elicits such an effect by inhibiting mammalian target of rapamycin complex 1 (mTORC1), the master regulator of cell proliferation and growth. Although recent studies have indi...

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Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Xiong, Mulin, Ferder, Ianina C, Ohguchi, Yasuyo, Wang, Ning
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825636/
https://ncbi.nlm.nih.gov/pubmed/26177380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1069928
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