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mTORC1 and p53: Clash of the gods?

A balance must be struck between cell growth and stress responses to ensure that cells proliferate without accumulating damaged DNA. This balance means that optimal cell proliferation requires the integration of pro-growth and stress-response pathways. mTOR (mechanistic target of rapamycin) is a ple...

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Detalhes bibliográficos
Main Authors: Hasty, Paul, Sharp, Zelton Dave, Curiel, Tyler J., Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570511/
https://ncbi.nlm.nih.gov/pubmed/23255104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22912
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