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Do p53 stress responses impact organismal aging?

p53 is a transcriptional regulator that responds to cellular stresses to suppress oncogenesis, but some of these responses can have unintended consequences that influence non-cancer-related aging processes. The impact of these consequences is not well understood—partly due to the many complex proces...

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Detalles Bibliográficos
Publicado en:Transl Cancer Res
Main Authors: Hasty, Paul, Campisi, Judith, Sharp, Z. Dave
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461382/
https://ncbi.nlm.nih.gov/pubmed/30984573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2016.12.02
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