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Inverse Thio Effects in the Hepatitis Delta Virus Ribozyme Reveal that the Reaction Pathway Is Controlled by Metal Ion Charge Density
[Image: see text] The hepatitis delta virus (HDV) ribozyme self-cleaves in the presence of a wide range of monovalent and divalent ions. Prior theoretical studies provided evidence that self-cleavage proceeds via a concerted or stepwise pathway, with the outcome dictated by the valency of the metal...
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| Publicat a: | Biochemistry |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2015
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824481/ https://ncbi.nlm.nih.gov/pubmed/25799319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00190 |
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