Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response

Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhao, Kai, Zhang, Meng, Zhang, Lei, Wang, Peng, Song, Guanhua, Liu, Bingyu, Wu, Haifeng, Yin, Zhinan, Gao, Chengjiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824456/
https://ncbi.nlm.nih.gov/pubmed/27026194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23771
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