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Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response

Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhao, Kai, Zhang, Meng, Zhang, Lei, Wang, Peng, Song, Guanhua, Liu, Bingyu, Wu, Haifeng, Yin, Zhinan, Gao, Chengjiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824456/
https://ncbi.nlm.nih.gov/pubmed/27026194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23771
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