Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824084/
https://ncbi.nlm.nih.gov/pubmed/26673710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1345
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