Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Methods Online
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824084/
https://ncbi.nlm.nih.gov/pubmed/26673710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1345
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