Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824084/
https://ncbi.nlm.nih.gov/pubmed/26673710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1345
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