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Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Publicado en:Stem Cell Res
Autores principales: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Hobbs, Carl, Stephenson, Emma, Ilic, Dusko
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823764/
https://ncbi.nlm.nih.gov/pubmed/27345979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.01.012
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