Generation of KCL028 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL028 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (43 trinucleotide repeats; 21 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Publicat a:Stem Cell Res
Autors principals: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Hobbs, Carl, Stephenson, Emma, Ilic, Dusko
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Lab Resource: Stem Cell Line
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823669/
https://ncbi.nlm.nih.gov/pubmed/27345983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.01.006
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