Generation of KCL036 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL036 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (38 trinucleotide repeats; 14 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res
Main Authors: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Hobbs, Carl, Stephenson, Emma, Ilic, Dusko
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
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Lab Resource: Stem Cell Line
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823766/
https://ncbi.nlm.nih.gov/pubmed/27346001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.02.026
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