Generation of KCL027 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL027 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (43 trinucleotide repeats; 21 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Vydáno v:Stem Cell Res
Hlavní autoři: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Hobbs, Carl, Stephenson, Emma, Ilic, Dusko
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Lab Resource: Stem Cell Line
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823767/
https://ncbi.nlm.nih.gov/pubmed/27345982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.01.008
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