Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Publicado no:Stem Cell Res
Main Authors: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Hobbs, Carl, Stephenson, Emma, Ilic, Dusko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Lab Resource: Stem Cell Line
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823764/
https://ncbi.nlm.nih.gov/pubmed/27345979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.01.012
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