Yüklüyor......
RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers
Bexarotene, a selective agonist for Retinoid X receptors (RXR) improves cognitive deficits and amyloid-β (Aβ) clearance in mice. Here we examine if the effect of bexarotene on RXR cistrome and transcriptomes depend on APOE isoform and Aβ deposition. We found bexarotene increased RXR binding to promo...
Kaydedildi:
| Yayımlandı: | Sci Rep |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823697/ https://ncbi.nlm.nih.gov/pubmed/27051978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24048 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|