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Role of prolyl hydroxylase domain proteins in the regulation of insulin secretion
Type 2 diabetes is associated with impaired nutrient‐regulated anaplerosis and insulin secretion in pancreatic β‐cells. One key anaplerotic substrate that may be involved in regulating insulin release is α‐ketoglutarate (αKG). Since prolyl hydroxylase domain proteins (PHDs) can metabolize cytosolic...
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| Publicado en: | Physiol Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823601/ https://ncbi.nlm.nih.gov/pubmed/26997627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12722 |
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