Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

Polycythemia is often associated with erythropoietin (EPO) overexpression and defective oxygen sensing. In normal cells, intracellular oxygen concentrations are directly sensed by prolyl hydroxylase domain (PHD)–containing proteins, which tag hypoxia-inducible factor (HIF) α subunits for polyubiquit...

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Detaylı Bibliyografya
Asıl Yazarlar: Takeda, Kotaro, Aguila, Hector L., Parikh, Nehal S., Li, Xiping, Lamothe, Katie, Duan, Li-Juan, Takeda, Hiromi, Lee, Frank S., Fong, Guo-Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Red Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265459/
https://ncbi.nlm.nih.gov/pubmed/18056838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-114561
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