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HIF-prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism
A classic response to systemic hypoxia is the increase in red blood cell production. This response is controlled by the prolyl hydroxylase domain/hypoxia-inducible factor (HIF) pathway, which regulates a broad spectrum of cellular functions. The discovery of this pathway as a key regulator of erythr...
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| Publicado no: | Hemodial Int |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526677/ https://ncbi.nlm.nih.gov/pubmed/28449418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hdi.12567 |
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