A carregar...

Hematological, Hepatic, and Retinal Phenotypes in Mice Deficient for Prolyl Hydroxylase Domain Proteins in the Liver

Prolyl hydroxylase domain (PHD) proteins catalyze oxygen-dependent prolyl hydroxylation of hypoxia-inducible factor 1α and 2α, tagging them for pVHL-dependent polyubiquitination and proteasomal degradation. In this study, albumin Cre (Alb(Cre))–mediated, hepatocyte-specific triple disruption of Phd1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Duan, Li-Juan, Takeda, Kotaro, Fong, Guo-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970000/
https://ncbi.nlm.nih.gov/pubmed/24508125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!