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Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease

Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an expanded polyglutamine tract in the huntingtin gene. Therapeutic approaches targeting mutant huntingtin (mtHtt) or its downstream toxic consequences are under development, including Rho kinase pathway inhibition. We investig...

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Bibliografische gegevens
Gepubliceerd in:Mol Neurobiol
Hoofdauteurs: Narayanan, K. Lakshmi, Chopra, Vanita, Rosas, H. Diana, Malarick, Keith, Hersch, Steven
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823347/
https://ncbi.nlm.nih.gov/pubmed/25941073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9147-9
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