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Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an expanded polyglutamine tract in the huntingtin gene. Therapeutic approaches targeting mutant huntingtin (mtHtt) or its downstream toxic consequences are under development, including Rho kinase pathway inhibition. We investig...
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| Publicado no: | Mol Neurobiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823347/ https://ncbi.nlm.nih.gov/pubmed/25941073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9147-9 |
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