Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Introduction: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...

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Vydáno v:Front Pharmacol
Hlavní autoři: Nour-Eldine, Wared, Ghantous, Crystal M., Zibara, Kazem, Dib, Leila, Issaa, Hawraa, Itani, Hana A., El-Zein, Nabil, Zeidan, Asad
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823273/
https://ncbi.nlm.nih.gov/pubmed/27092079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00086
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