Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Introduction: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...

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Publicat a:Front Pharmacol
Autors principals: Nour-Eldine, Wared, Ghantous, Crystal M., Zibara, Kazem, Dib, Leila, Issaa, Hawraa, Itani, Hana A., El-Zein, Nabil, Zeidan, Asad
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823273/
https://ncbi.nlm.nih.gov/pubmed/27092079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00086
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