Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Introduction: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Nour-Eldine, Wared, Ghantous, Crystal M., Zibara, Kazem, Dib, Leila, Issaa, Hawraa, Itani, Hana A., El-Zein, Nabil, Zeidan, Asad
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823273/
https://ncbi.nlm.nih.gov/pubmed/27092079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00086
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