Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Introduction: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Nour-Eldine, Wared, Ghantous, Crystal M., Zibara, Kazem, Dib, Leila, Issaa, Hawraa, Itani, Hana A., El-Zein, Nabil, Zeidan, Asad
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823273/
https://ncbi.nlm.nih.gov/pubmed/27092079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00086
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