Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation

Glucose fermentation through glycolysis even in the presence of oxygen (Warburg effect) is a common feature of cancer cells increasingly considered as an enticing target in clinical development. This study aimed to analyze the link between metabolism, energy stores and proliferation rates in cancer...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: De Preter, Géraldine, Neveu, Marie-Aline, Danhier, Pierre, Brisson, Lucie, Payen, Valéry L., Porporato, Paolo E., Jordan, Bénédicte F., Sonveaux, Pierre, Gallez, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823080/
https://ncbi.nlm.nih.gov/pubmed/26543237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6272
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