Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation

Glucose fermentation through glycolysis even in the presence of oxygen (Warburg effect) is a common feature of cancer cells increasingly considered as an enticing target in clinical development. This study aimed to analyze the link between metabolism, energy stores and proliferation rates in cancer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: De Preter, Géraldine, Neveu, Marie-Aline, Danhier, Pierre, Brisson, Lucie, Payen, Valéry L., Porporato, Paolo E., Jordan, Bénédicte F., Sonveaux, Pierre, Gallez, Bernard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823080/
https://ncbi.nlm.nih.gov/pubmed/26543237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6272
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