Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation

Glucose fermentation through glycolysis even in the presence of oxygen (Warburg effect) is a common feature of cancer cells increasingly considered as an enticing target in clinical development. This study aimed to analyze the link between metabolism, energy stores and proliferation rates in cancer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: De Preter, Géraldine, Neveu, Marie-Aline, Danhier, Pierre, Brisson, Lucie, Payen, Valéry L., Porporato, Paolo E., Jordan, Bénédicte F., Sonveaux, Pierre, Gallez, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823080/
https://ncbi.nlm.nih.gov/pubmed/26543237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6272
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