Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models

Reverting glycolytic metabolism is an attractive strategy for cancer therapy as upregulated glycolysis is a hallmark in various cancers. Dichloroacetate (DCA), long used to treat lactic acidosis in various pathologies, has emerged as a promising anti-cancer drug. By inhibiting the pyruvate dehydroge...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Neveu, Marie-Aline, Preter, Géraldine De, Joudiou, Nicolas, Bol, Anne, Brender, Jeffery R., Saito, Keita, Kishimoto, Shun, Grégoire, Vincent, Jordan, Bénédicte F., Krishna, Murali C., Feron, Olivier, Gallez, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340254/
https://ncbi.nlm.nih.gov/pubmed/28082726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13176
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