The Blood Flow Shutdown Induced by Combretastatin A4 Impairs Gemcitabine Delivery in a Mouse Hepatocarcinoma

In recent clinical studies, vascular disrupting agents (VDAs) are mainly used in combination with chemotherapy. However, an often overlooked concern in treatment combination is the VDA-induced impairment of chemotherapy distribution in the tumor. The work presented here investigated the impact of bl...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Fruytier, Anne-Catherine, Le Duff, Cecile S., Po, Chrystelle, Magat, Julie, Bouzin, Caroline, Neveu, Marie-Aline, Feron, Olivier, Jordan, Benedicte F., Gallez, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179558/
https://ncbi.nlm.nih.gov/pubmed/28066252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00506
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