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Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks
Accurate repair of DNA double-strand breaks (DSB) caused during DNA replication and by exogenous stresses is critical for the maintenance of genomic integrity. There is growing evidence that the Polo-like kinase 1 (Plk1) that plays a number of pivotal roles in cell proliferation can directly partici...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823034/ https://ncbi.nlm.nih.gov/pubmed/26745677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6825 |
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