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Distinct functions of BRCA1 and BRCA2 in double-strand break repair
Individuals carrying BRCA mutations are predisposed to breast cancer. The BRCA1 and BRCA2 proteins are required for homologous recombination and DNA break repair, leading to the suggestion that they act in concert. However, direct evidence of a stable BRCA1/BRCA2 complex has not been demonstrated. R...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138716/ https://ncbi.nlm.nih.gov/pubmed/11879553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr417 |
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