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Distinct functions of BRCA1 and BRCA2 in double-strand break repair

Individuals carrying BRCA mutations are predisposed to breast cancer. The BRCA1 and BRCA2 proteins are required for homologous recombination and DNA break repair, leading to the suggestion that they act in concert. However, direct evidence of a stable BRCA1/BRCA2 complex has not been demonstrated. R...

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Detalles Bibliográficos
Publicado en:Breast Cancer Res
Principais autores: Liu, Yilun, West, Stephen C
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2001
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138716/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11879553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr417
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