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Distinct functions of BRCA1 and BRCA2 in double-strand break repair

Individuals carrying BRCA mutations are predisposed to breast cancer. The BRCA1 and BRCA2 proteins are required for homologous recombination and DNA break repair, leading to the suggestion that they act in concert. However, direct evidence of a stable BRCA1/BRCA2 complex has not been demonstrated. R...

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Detaylı Bibliyografya
Yayımlandı:Breast Cancer Res
Asıl Yazarlar: Liu, Yilun, West, Stephen C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138716/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11879553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr417
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