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Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer
Here we report a peptide-MHC (pMHC) dodecamer as a “next generation” technology that is a significantly more sensitive and versatile alternative to pMHC tetramers for the detection, isolation, and phenotypic analysis of antigen-specific T cells. In particular, dodecamers are able to detect two- to f...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822615/ https://ncbi.nlm.nih.gov/pubmed/26979955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602488113 |
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