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A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells
We have developed a single-molecule imaging technique that uses quantum dot-labeled peptide-major histocompatibility complex (pMHC) ligands to study CD4(+) T cell functional sensitivity. We found that naive T cells, T cell blasts and memory T cells could all be triggered by a single pMHC to secrete...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846396/ https://ncbi.nlm.nih.gov/pubmed/24120362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.036 |
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