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Ligand recognition during thymic development and γδ T cell function specification
γδ T cells develop in the thymus before entering the periphery. Recent work suggests that thymic development does little to constrain γδ T cell antigen specificities, but instead determines their effector fate. When triggered through the T cell receptor, ligand-naïve γδ T cells produce IL-17, ligand...
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Autores principales: | , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906674/ https://ncbi.nlm.nih.gov/pubmed/20430644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.002 |
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