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Thymic maturation determines γδ T cell function, but not their antigen specificities

γδ T cells contribute uniquely to host immune defense, but how they do so remains unclear. Recent work suggests that thymic selection does little to constrain γδ T cell antigen specificities, but instead determines their effector fate. When triggered through the T cell receptor, ligand-experienced c...

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Detalhes bibliográficos
Main Authors: Jensen, Kirk D. C., Chien, Yueh-hsiu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697822/
https://ncbi.nlm.nih.gov/pubmed/19321327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.02.008
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