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Ligand recognition during thymic development and γδ T cell function specification

γδ T cells develop in the thymus before entering the periphery. Recent work suggests that thymic development does little to constrain γδ T cell antigen specificities, but instead determines their effector fate. When triggered through the T cell receptor, ligand-naïve γδ T cells produce IL-17, ligand...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Meyer, Christina, Zeng, Xun, Chien, Yueh-hsiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906674/
https://ncbi.nlm.nih.gov/pubmed/20430644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.002
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