A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells

We have developed a single-molecule imaging technique that uses quantum dot-labeled peptide-major histocompatibility complex (pMHC) ligands to study CD4(+) T cell functional sensitivity. We found that naive T cells, T cell blasts and memory T cells could all be triggered by a single pMHC to secrete...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Huang, Jun, Brameshuber, Mario, Zeng, Xun, Xie, Jianming, Li, Qi-jing, Chien, Yueh-hsiu, Valitutti, Salvatore, Davis, Mark M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846396/
https://ncbi.nlm.nih.gov/pubmed/24120362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.036
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares