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The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy

More than 15 years ago the serial engagement model was proposed as an attempt to solve the low affinity/high sensitivity paradox of TCR antigen recognition. Since then, the model has undergone ups and downs marked by the technical and conceptual advancements made in the field of T lymphocyte activat...

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Detalhes bibliográficos
Autor principal: Valitutti, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428561/
https://ncbi.nlm.nih.gov/pubmed/22973273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00272
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