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The receptor deformation model of TCR triggering

Through T cell receptors (TCRs), T cells can detect and respond to very small numbers of foreign peptides among a huge number of self-peptides presented by major histocompatibility complexes (pMHCs) on the surface of antigen-presenting cells (APCs). How T cells achieve such remarkable sensitivity an...

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Détails bibliographiques
Auteurs principaux: Ma, Zhengyu, Janmey, Paul A., Finkel, Terri H.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679516/
https://ncbi.nlm.nih.gov/pubmed/17984179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-9331hyp
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