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Surface-Anchored Monomeric Agonist pMHCs Alone Trigger TCR with High Sensitivity
At the interface between T cell and antigen-presenting cell (APC), peptide antigen presented by MHC (pMHC) binds to the T cell receptor (TCR) and initiates signaling. The mechanism of TCR signal initiation, or triggering, remains unclear. An interesting aspect of this puzzle is that although soluble...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253636/ https://ncbi.nlm.nih.gov/pubmed/18303949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060043 |
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