TCR Triggering by pMHC Ligands Tethered on Surfaces via Poly(Ethylene Glycol) Depends on Polymer Length

Antigen recognition by T cells relies on the interaction between T cell receptor (TCR) and peptide-major histocompatibility complex (pMHC) at the interface between the T cell and the antigen presenting cell (APC). The pMHC-TCR interaction is two-dimensional (2D), in that both the ligand and receptor...

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Pubblicato in:PLoS One
Autori principali: Ma, Zhengyu, LeBard, David N., Loverde, Sharon M., Sharp, Kim A., Klein, Michael L., Discher, Dennis E., Finkel, Terri H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226474/
https://ncbi.nlm.nih.gov/pubmed/25383949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112292
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