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Degradation of  T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation

T cell activation by specific antigen results in a rapid and long-lasting downregulation of triggered T cell receptors (TCRs). In this work, we investigated the fate of downregulated TCR– CD3-ζ complexes. T cells stimulated by peptide-pulsed antigen-presenting cells (APCs) undergo an antigen dose-de...

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Autors principals: Valitutti, Salvatore, Müller, Sabina, Salio, Mariolina, Lanzavecchia, Antonio
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196323/
https://ncbi.nlm.nih.gov/pubmed/9151711
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