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Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein

An important component of the activity of p53 as a tumor suppressor is its interaction with the transcriptional coactivators cyclic-AMP response element-binding protein (CREB)-binding protein (CBP) and p300, which activate transcription of p53-regulated stress response genes and stabilize p53 agains...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Krois, Alexander S., Ferreon, Josephine C., Martinez-Yamout, Maria A., Dyson, H. Jane, Wright, Peter E.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822595/
https://ncbi.nlm.nih.gov/pubmed/26976603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602487113
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