Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

Methylation of CpG dinucleotides in DNA is a common epigenetic modification in eukaryotes that plays a central role in maintenance of genome stability, gene silencing, genomic imprinting, development, and disease. Kaiso, a bifunctional Cys(2)His(2) zinc finger protein implicated in tumor-cell prolif...

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Autors principals: Buck-Koehntop, Bethany A., Stanfield, Robyn L., Ekiert, Damian C., Martinez-Yamout, Maria A., Dyson, H. Jane, Wilson, Ian A., Wright, Peter E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458336/
https://ncbi.nlm.nih.gov/pubmed/22949637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213726109
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