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Kaiso uses all Three Zinc Fingers and Adjacent Sequence Motifs for High Affinity Binding to Sequence-specific and Methyl-CpG DNA Targets
Kaiso is a Cys(2)His(2) zinc finger protein that mediates methyl-CpG -dependent and sequence-specific transcriptional repression. As a first step towards elucidating the structural and molecular basis for recognition of these disparate DNA sequences, the minimal binding region of Kaiso was identifie...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309074/ https://ncbi.nlm.nih.gov/pubmed/22300642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.045 |
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