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A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences
Recognition of the epigenetic mark 5-methylcytosine (mC) at CpG sites in DNA has emerged as a novel function of many eukaryotic transcription factors (TFs). It remains unclear why the sequence specificity of these TFs differs for CpG-methylated motifs and consensus motifs. Here, we dissect the struc...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7253346/ https://ncbi.nlm.nih.gov/pubmed/32352758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00253 |
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