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Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

Environmental factors, including pesticides, have been linked to autism and neurodegeneration risk using retrospective epidemiological studies. Here we sought to prospectively identify chemicals that share transcriptomic signatures with neurological disorders, by exposing mouse cortical neuron-enric...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Pearson, Brandon L., Simon, Jeremy M., McCoy, Eric S., Salazar, Gabriela, Fragola, Giulia, Zylka, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821887/
https://ncbi.nlm.nih.gov/pubmed/27029645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11173
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